Drug class

Butyrophenones

Butyrophenones are a distinct chemical class of first-generation neuroleptic agents that primarily act as potent antagonists at postsynaptic dopamine D2 receptors in the central nervous system. Read more about Butyrophenones

48 drugs in this class 40 manufacturers

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Drugs in Butyrophenones

Showing 1–9 of 48 drugs

HALOPERIDOL

ANTIPSYCHOTICS · SCHIZOPHRENIA ·+2
Mylan Pharmaceuticals

HALOPERIDOL

ANTIPSYCHOTICS · SCHIZOPHRENIA ·+2
MYLAN INSTITUTI

DROPERIDOL

ANTIEMETIC · POST-OPERATIVE NAUSEA AND VOMITING ·+1
American Regent
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About Butyrophenones.

Butyrophenones are a distinct chemical class of first-generation neuroleptic agents that primarily act as potent antagonists at postsynaptic dopamine D2 receptors in the central nervous system.

By blocking dopaminergic signaling in mesolimbic pathways and the chemoreceptor trigger zone, these medications reduce psychotic symptoms and exert antiemetic and sedative effects.

Clinically, drugs within this class—most notably haloperidol and droperidol—are widely utilized in psychiatry and acute care for the management of schizophrenia, acute psychotic agitation, Tourette syndrome, and postoperative nausea and vomiting.