Drug class

Chemoprotectives - Agents for Chemotherapy Extravasation

The phrase "Chemoprotectives - Agents for Chemotherapy Extravasation" refers to an administrative drug classification rather than a formal standalone pharmacologic class, encompassing antidote and cytoprotective therapies used to mitigate local tissue damage following accidental extravasation of vesicant antineoplastic drugs. Read more about Chemoprotectives - Agents for Chemotherapy Extravasation

11 drugs in this class 10 manufacturers

Advertisement

Drugs in Chemoprotectives - Agents for Chemotherapy Extravasation

Showing 1–9 of 11 drugs

DEXRAZOXANE (dexrazoxane HCl)

CHEMOPROTECTIVES - CARDIOPROTECTIVE INTRACELLULAR CHELATORS · DOXORUBICIN-INDUCED CARDIOMYOPATHY
Hikma Pharmaceuticals USA

DEXRAZOXANE HCL

CHEMOPROTECTIVES - CARDIOPROTECTIVE INTRACELLULAR CHELATORS · DOXORUBICIN-INDUCED CARDIOMYOPATHY
FOSUN PHARMA US

TOTECT (dexrazoxane HCl)

CHEMOPROTECTIVES - CARDIOPROTECTIVE INTRACELLULAR CHELATORS · DOXORUBICIN-INDUCED CARDIOMYOPATHY ·+1
CLINIGEN GROUP
Filter & compare in the drug finder → Opens the drug finder with Chemoprotectives - Agents for Chemotherapy Extravasation preselected. Add indication or manufacturer filters there.

About Chemoprotectives - Agents for Chemotherapy Extravasation.

The phrase "Chemoprotectives - Agents for Chemotherapy Extravasation" refers to an administrative drug classification rather than a formal standalone pharmacologic class, encompassing antidote and cytoprotective therapies used to mitigate local tissue damage following accidental extravasation of vesicant antineoplastic drugs.

The primary therapeutic agent in this category is dexrazoxane, an intracellular chelating agent and topoisomerase II inhibitor that prevents anthracycline-mediated tissue necrosis.

Additional supportive agents, such as hyaluronidase or sodium thiosulfate, function enzymatically or chemically to disperse or neutralize extravasated vinca alkaloids or alkylating agents.

These therapies are utilized specifically in oncology supportive care to manage accidental perivascular infiltration during the treatment of various solid tumors and hematologic malignancies.