Cholinesterase Inhibitors

Cholinesterase inhibitors are a therapeutic class of agents that prevent the enzymatic breakdown of acetylcholine by inhibiting acetylcholinesterase and, in some cases, butyrylcholinesterase Centrally active agents are primarily utilized for symptomatic management of cognitive impairment in neurodegenerative conditions such as Alzheimer disease and Parkinson disease dementia

Cholinesterase inhibitors are a therapeutic class of agents that prevent the enzymatic breakdown of acetylcholine by inhibiting acetylcholinesterase and, in some cases, butyrylcholinesterase

By slowing degradation, these medications augment synaptic concentrations of acetylcholine and prolong cholinergic neurotransmission in both the central and peripheral nervous systems

By slowing degradation, these medications augment synaptic concentrations of acetylcholine and prolong cholinergic neurotransmission in both the central and peripheral nervous systems Centrally active agents are primarily utilized for symptomatic management of cognitive impairment in neurodegenerative conditions such as Alzheimer disease and Parkinson disease dementia Peripherally acting agents within this class are utilized in neuromuscular disorders such as myasthenia gravis and for perioperat...

By slowing degradation, these medications augment synaptic concentrations of acetylcholine and prolong cholinergic neurotransmission in both the central and peripheral nervous systems Peripherally acting agents within this class are utilized in neuromuscular disorders such as myasthenia gravis and for perioperative reversal of non-depolarizing neuromuscular blockade