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Fibric Acid Derivatives

Fibric acid derivatives, commonly referred to as fibrates, are a class of lipid-lowering medications that include agents such as gemfibrozil and fenofibrate. Read more about Fibric Acid Derivatives

86 drugs in this class 57 manufacturers

Related classes & indications

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Showing 64–72 of 86 drugs

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FENOFIBRIC ACID (fenofibric acid (choline))

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

AUROBINDO PHARM

FENOFIBRIC ACID

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

PALMETTO PHARMA

FENOFIBRIC ACID (fenofibric acid (choline))

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

LEADING PHARMA

FENOFIBRATE

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

WESTMINSTER PHA

FENOFIBRIC ACID (fenofibric acid (choline))

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

SLATE RUN PHARM

FENOFIBRATE

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

LIFESTAR PHARMA

GEMFIBROZIL

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

DENTON PHARMA I

GEMFIBROZIL

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

APHENA PHARMA S

GEMFIBROZIL

FIBRIC ACID DERIVATIVES · HYPERTRIGLYCERIDEMIA ·+1

XLCARE PHARMACE

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About Fibric Acid Derivatives.

Fibric acid derivatives, commonly referred to as fibrates, are a class of lipid-lowering medications that include agents such as gemfibrozil and fenofibrate.

They function primarily as agonists of the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha), which alters the transcription of genes regulating lipoprotein metabolism, enhances lipoprotein lipase activity, stimulates cellular fatty acid beta-oxidation, and substantially decreases circulating plasma triglycerides while modestly increasing high-density lipoprotein cholesterol.

Clinically, these agents are primarily indicated as adjuncts to diet for the treatment of severe hypertriglyceridemia—often to reduce the risk of acute pancreatitis—and are also utilized in the management of mixed dyslipidemia and primary hypercholesterolemia.

nih.gov
Fibric acid derivatives, commonly referred to as fibrates, are a class of lipid-lowering medications that include agents such as gemfibrozil and fenofibrate Clinically, these agents are primarily indicated as adjuncts to diet for the treatment of severe hypertriglyceridemia—often to reduce the risk of acute pancreatitis—and are also utilized in the management of mixed dyslipidemia and primary hypercholesterolemia
nih.gov
Fibric acid derivatives, commonly referred to as fibrates, are a class of lipid-lowering medications that include agents such as gemfibrozil and fenofibrate
fda.gov
They function primarily as agonists of the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha), which alters the transcription of genes regulating lipoprotein metabolism, enhances lipoprotein lipase activity, stimulates cellular fatty acid beta-oxidation, and substantially decreases circulating plasma triglycerides while modestly increasing high-density lipoprotein cholesterol Clinically, these agents are primarily indicated as adjuncts to diet for the treatment of sev...
nih.gov
They function primarily as agonists of the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha), which alters the transcription of genes regulating lipoprotein metabolism, enhances lipoprotein lipase activity, stimulates cellular fatty acid beta-oxidation, and substantially decreases circulating plasma triglycerides while modestly increasing high-density lipoprotein cholesterol