Drug class

Growth Hormone Modulators

The term "growth hormone modulators" is a broad pharmacological descriptor rather than a single standardized FDA drug class, encompassing agents that alter the somatotropic (growth hormone/insulin-like growth factor-1) axis. Read more about Growth Hormone Modulators

19 drugs in this class 11 manufacturers

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Drugs in Growth Hormone Modulators

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About Growth Hormone Modulators.

The term "growth hormone modulators" is a broad pharmacological descriptor rather than a single standardized FDA drug class, encompassing agents that alter the somatotropic (growth hormone/insulin-like growth factor-1) axis.

This category includes recombinant human growth hormone agonists (such as somatropin) that stimulate growth hormone receptors, growth hormone receptor antagonists (such as pegvisomant) that block peripheral receptor activation, and hypothalamic releasing-factor analogs that regulate endogenous hormone secretion.

Therapeutically, these agents are primarily indicated to manage pediatric and adult growth hormone deficiencies, short stature associated with conditions like Turner syndrome, and catabolic or wasting states, as well as to treat disorders of growth hormone excess such as acromegaly.