Drug class

Hyaluronidase Enzymes

Hyaluronidase enzymes are a therapeutic class of endoglycosidases that transiently hydrolyze hyaluronic acid, a primary polysaccharide component of the interstitial extracellular matrix. Read more about Hyaluronidase Enzymes

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Drugs in Hyaluronidase Enzymes

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AMPHADASE (hyaluronidase)

HYALURONIDASE ENZYMES · ADJUNCT TREATMENT TO INCREASE ABSORPTION AND DISPERSION OF OTHER INJECTED DRUGS ·+2
Amphastar Pharmaceuticals
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About Hyaluronidase Enzymes.

Hyaluronidase enzymes are a therapeutic class of endoglycosidases that transiently hydrolyze hyaluronic acid, a primary polysaccharide component of the interstitial extracellular matrix.

By temporarily lowering tissue viscosity and opening interstitial space, these enzymes function as permeation and spreading adjuvants to enhance the systemic absorption and dispersion of co-administered fluids and therapeutic agents.

Clinically, they are used to facilitate subcutaneous hydration through hypodermoclysis, enhance the diffusion of local anesthetics in ophthalmology and regional nerve blocks, and enable subcutaneous delivery of high-volume biologics in oncology and immunology.