SIROLIMUS
IMMUNOSUPPRESSANTS - MTOR INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
CAMBER PHARMACE
Drug class
Immunosuppressants - Calcineurin and mTOR Inhibitors
The phrase "Immunosuppressants - Calcineurin and mTOR Inhibitors" represents an administrative grouping of two distinct pharmacologic classes—calcineurin inhibitors (such as tacrolimus and cyclosporine) and mechanistic target of rapamycin (mTOR) inhibitors (such as sirolimus and everolimus)—rather than a single unified therapeutic class. Read more about Immunosuppressants - Calcineurin and mTOR Inhibitors
86 drugs in this class 54 manufacturers
Drugs in Immunosuppressants - Calcineurin and mTOR Inhibitors
TACROLIMUS
IMMUNOSUPPRESSANTS - CALCINEURIN INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+3
APHENA PHARMA S
EVEROLIMUS
ANTINEOPLASTIC - MTOR KINASE INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
PAR HEALTH USA,
SIROLIMUS
IMMUNOSUPPRESSANTS - MTOR INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
AVPAK
EVEROLIMUS
ANTINEOPLASTIC - MTOR KINASE INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
BRECKENRIDGE
TACROLIMUS
IMMUNOSUPPRESSANTS - CALCINEURIN INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+3
BPI LABS, LLC
TACROLIMUS
IMMUNOSUPPRESSANTS - CALCINEURIN INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+3
A-S MEDICATION
TACROLIMUS
IMMUNOSUPPRESSANTS - CALCINEURIN INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+3
GSMS, INC.
SIROLIMUS
IMMUNOSUPPRESSANTS - MTOR INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
APOTEX CORP
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The phrase "Immunosuppressants - Calcineurin and mTOR Inhibitors" represents an administrative grouping of two distinct pharmacologic classes—calcineurin inhibitors (such as tacrolimus and cyclosporine) and mechanistic target of rapamycin (mTOR) inhibitors (such as sirolimus and everolimus)—rather than a single unified therapeutic class.
Both drug categories function by disrupting intracellular signaling essential for T-lymphocyte activation and proliferation, with calcineurin inhibitors blocking cytokine transcription such as interleukin-2, and mTOR inhibitors blocking downstream cell-cycle progression.
Clinically, these agents are primarily used to prevent allograft rejection in solid organ transplantation, as well as to treat graft-versus-host disease and select severe autoimmune or inflammatory disorders.
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nih.gov
The phrase "Immunosuppressants - Calcineurin and mTOR Inhibitors" represents an administrative grouping of two distinct pharmacologic classes—calcineurin inhibitors (such as tacrolimus and cyclosporine) and mechanistic target of rapamycin (mTOR) inhibitors (such as sirolimus and everolimus) Both drug categories function by disrupting intracellular signaling essential for T-lymphocyte activation and proliferation, with calcineurin inhibitors blocking cytokine transcription such as interleukin-2, ...
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jebms.org
The phrase "Immunosuppressants - Calcineurin and mTOR Inhibitors" represents an administrative grouping of two distinct pharmacologic classes—calcineurin inhibitors (such as tacrolimus and cyclosporine) and mechanistic target of rapamycin (mTOR) inhibitors (such as sirolimus and everolimus)
-
immunologyresearchjournal.com
Both drug categories function by disrupting intracellular signaling essential for T-lymphocyte activation and proliferation, with calcineurin inhibitors blocking cytokine transcription such as interleukin-2, and mTOR inhibitors blocking downstream cell-cycle progression
-
youtube.com
Clinically, these agents are primarily used to prevent allograft rejection in solid organ transplantation, as well as to treat graft-versus-host disease and select severe autoimmune or inflammatory disorders
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