Drug class

Nasal Antihistamines

Nasal antihistamines are a therapeutic drug class consisting of topical formulations—such as azelastine and olopatadine—administered directly into the nasal passages to treat upper respiratory tract symptoms. Read more about Nasal Antihistamines

33 drugs in this class 23 manufacturers

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Drugs in Nasal Antihistamines

Showing 19–27 of 33 drugs

AZELASTINE HCL

NASAL ANTIHISTAMINES · VASOMOTOR RHINITIS ·+2
A-S MEDICATION

AZELASTINE HCL

NASAL ANTIHISTAMINES · VASOMOTOR RHINITIS ·+2
PROFICIENT RX L

OLOPATADINE HCL

NASAL ANTIHISTAMINES · ALLERGIC RHINITIS ·+1
BRYANT RANCH PR

AZELASTINE HCL

NASAL ANTIHISTAMINES · VASOMOTOR RHINITIS ·+2
AUROBINDO PHARM
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About Nasal Antihistamines.

Nasal antihistamines are a therapeutic drug class consisting of topical formulations—such as azelastine and olopatadine—administered directly into the nasal passages to treat upper respiratory tract symptoms.

They act primarily by competitively antagonizing peripheral H1 receptors on effector cells within the nasal mucosa, inhibiting histamine-mediated vasodilation, vascular permeability, and sensory nerve stimulation, while also demonstrating secondary local anti-inflammatory properties.

Clinically, they are indicated for the management of seasonal and perennial allergic rhinitis, as well as nonallergic vasomotor rhinitis, providing rapid targeted relief from rhinorrhea, sneezing, nasal pruritus, and nasal congestion with lower systemic exposure than oral alternatives.