Drug class
Nitroimidazole Vaginal
The term "Nitroimidazole Vaginal" designates a route-specific administrative grouping rather than a distinct standalone pharmacological class, referring to intravaginal formulations of nitroimidazole antimicrobial agents, most notably metronidazole. Read more about Nitroimidazole Vaginal
12 drugs in this class 11 manufacturers
Drugs in Nitroimidazole Vaginal
METRONIDAZOLE
METRONIDAZOLE
The term "Nitroimidazole Vaginal" designates a route-specific administrative grouping rather than a distinct standalone pharmacological class, referring to intravaginal formulations of nitroimidazole antimicrobial agents, most notably metronidazole.
These agents enter microbial cells and undergo intracellular reduction to generate reactive nitro radical intermediates that damage DNA and inhibit nucleic acid synthesis in susceptible anaerobic pathogens.
Formulated as gels or suppositories to provide localized therapy with reduced systemic absorption, they are primarily indicated for the treatment of bacterial vaginosis in female patients.
Systemic administration is generally required for other nitroimidazole indications, such as trichomoniasis, due to lower eradication rates with topical vaginal delivery alone.
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epocrates.com
The term "Nitroimidazole Vaginal" designates a route-specific administrative grouping rather than a distinct standalone pharmacological class, referring to intravaginal formulations of nitroimidazole antimicrobial agents, most notably metronidazole Formulated as gels or suppositories to provide localized therapy with reduced systemic absorption, they are primarily indicated for the treatment of bacterial vaginosis in female patients
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fda.gov
The term "Nitroimidazole Vaginal" designates a route-specific administrative grouping rather than a distinct standalone pharmacological class, referring to intravaginal formulations of nitroimidazole antimicrobial agents, most notably metronidazole
-
fda.gov
These agents enter microbial cells and undergo intracellular reduction to generate reactive nitro radical intermediates that damage DNA and inhibit nucleic acid synthesis in susceptible anaerobic pathogens
-
nih.gov
Formulated as gels or suppositories to provide localized therapy with reduced systemic absorption, they are primarily indicated for the treatment of bacterial vaginosis in female patients
-
nih.gov
Systemic administration is generally required for other nitroimidazole indications, such as trichomoniasis, due to lower eradication rates with topical vaginal delivery alone
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