Drug class

Nitrosoureas

Nitrosoureas are a distinct class of lipophilic alkylating antineoplastic agents that exert cytotoxic effects by alkylating and cross-linking DNA, thereby inhibiting nucleic acid synthesis and cell division. Read more about Nitrosoureas

18 drugs in this class 16 manufacturers

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Drugs in Nitrosoureas

Showing 1–9 of 18 drugs

CARMUSTINE

NITROSOUREAS · MALIGNANT BRAIN NEOPLASM ·+6
AMNEAL BIOSCIEN

CARMUSTINE

NITROSOUREAS · MALIGNANT BRAIN NEOPLASM ·+6
ZYDUS PHARMACEU

CARMUSTINE

NITROSOUREAS · MALIGNANT BRAIN NEOPLASM ·+6
STI PHARMA, LLC

CARMUSTINE

NITROSOUREAS · MALIGNANT BRAIN NEOPLASM ·+6
DR.REDDY'S LAB

CARMUSTINE

NITROSOUREAS · MALIGNANT BRAIN NEOPLASM ·+6
ALEMBIC PHARMAC
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About Nitrosoureas.

Nitrosoureas are a distinct class of lipophilic alkylating antineoplastic agents that exert cytotoxic effects by alkylating and cross-linking DNA, thereby inhibiting nucleic acid synthesis and cell division.

Due to their marked lipid solubility, agents such as carmustine and lomustine readily cross the blood-brain barrier, making them clinically important therapies for central nervous system malignancies, including high-grade gliomas and brain metastases.

They are also utilized, often in combination regimens, to treat lymphomas, multiple myeloma, and, in the case of streptozocin, pancreatic neuroendocrine islet cell tumors.