Ophthalmic - Anti-Inflammatory, Immunomodulators

Ophthalmic anti-inflammatory immunomodulators are a therapeutic drug class used in formulary classifications and clinical practice guidelines to describe topical ocular agents that attenuate immune-driven ocular surface inflammation Their primary therapeutic applications include chronic dry eye disease (keratoconjunctivitis sicca) and severe allergic ocular surface disorders, such as vernal keratoconjunctivitis

Ophthalmic anti-inflammatory immunomodulators are a therapeutic drug class used in formulary classifications and clinical practice guidelines to describe topical ocular agents that attenuate immune-driven ocular surface inflammation

Represented primarily by calcineurin inhibitors, such as ophthalmic cyclosporine, and lymphocyte function-associated antigen-1 antagonists like lifitegrast, these agents work locally by inhibiting T-cell activation, migration, and the downstream release of proinflammatory cytokines

Represented primarily by calcineurin inhibitors, such as ophthalmic cyclosporine, and lymphocyte function-associated antigen-1 antagonists like lifitegrast, these agents work locally by inhibiting T-cell activation, migration, and the downstream release of proinflammatory cytokines

Represented primarily by calcineurin inhibitors, such as ophthalmic cyclosporine, and lymphocyte function-associated antigen-1 antagonists like lifitegrast, these agents work locally by inhibiting T-cell activation, migration, and the downstream release of proinflammatory cytokines By dampening local immune activity, they restore ocular surface homeostasis and improve functional tear production

By dampening local immune activity, they restore ocular surface homeostasis and improve functional tear production

Their primary therapeutic applications include chronic dry eye disease (keratoconjunctivitis sicca) and severe allergic ocular surface disorders, such as vernal keratoconjunctivitis