Drug class

Ophthalmic Carbonic Anhydrase Inhibitors

Ophthalmic carbonic anhydrase inhibitors are a class of topical ocular medications, including dorzolamide and brinzolamide, used to reduce intraocular pressure. Read more about Ophthalmic Carbonic Anhydrase Inhibitors

47 drugs in this class 22 manufacturers

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Drugs in Ophthalmic Carbonic Anhydrase Inhibitors

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DORZOLAMIDE HCL

OPHTHALMIC CARBONIC ANHYDRASE INHIBITORS · OCULAR HYPERTENSION ·+1
SANDOZ
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About Ophthalmic Carbonic Anhydrase Inhibitors.

Ophthalmic carbonic anhydrase inhibitors are a class of topical ocular medications, including dorzolamide and brinzolamide, used to reduce intraocular pressure.

They function by inhibiting the enzyme carbonic anhydrase within the ciliary body epithelium, which slows bicarbonate ion synthesis and subsequently decreases aqueous humor production and fluid transport.

Therapeutically, these agents are primarily indicated for the management of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension, either as monotherapy or as adjunctive therapy with other intraocular pressure-lowering agents.

By delivering targeted local enzyme inhibition, they minimize many of the systemic adverse effects traditionally associated with oral carbonic anhydrase inhibitors while mitigating the risk of progressive glaucomatous optic nerve damage.