Ophthalmic Local Anesthetics

Ophthalmic local anesthetics are a specialized class of rapid-onset, short-acting agents formulated for direct topical administration to the ocular surface In clinical practice, these agents are primarily indicated for facilitating short diagnostic evaluations and minor interventional procedures, such as tonometry, gonioscopy, foreign body removal, corneal scraping, and minor surgical manipulations of the ocular surface Because inappropriate or repeated self-administration carries a high risk of...

Ophthalmic local anesthetics are a specialized class of rapid-onset, short-acting agents formulated for direct topical administration to the ocular surface They produce reversible surface anesthesia by stabilizing neuronal cell membranes and reversibly blocking voltage-gated sodium channels, thereby preventing the initiation and propagation of nerve impulses in the cornea and conjunctiva

They produce reversible surface anesthesia by stabilizing neuronal cell membranes and reversibly blocking voltage-gated sodium channels, thereby preventing the initiation and propagation of nerve impulses in the cornea and conjunctiva

Because inappropriate or repeated self-administration carries a high risk of severe corneal epithelial toxicity and permanent ocular injury, they are restricted to direct in-office use by healthcare professionals