Drug class

Oral Antivirals for Chronic Hepatitis B

Oral antivirals for chronic hepatitis B primarily consist of nucleoside and nucleotide analogues, including agents such as entecavir, tenofovir disoproxil fumarate, and tenofovir alafenamide. Read more about Oral Antivirals for Chronic Hepatitis B

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About Oral Antivirals for Chronic Hepatitis B.

Oral antivirals for chronic hepatitis B primarily consist of nucleoside and nucleotide analogues, including agents such as entecavir, tenofovir disoproxil fumarate, and tenofovir alafenamide.

These agents function by selectively inhibiting the reverse transcriptase and DNA polymerase activities of the hepatitis B virus, thereby causing viral DNA chain termination and suppressing replication.

Clinically, they are used to manage chronic hepatitis B virus infection to achieve long-term viral suppression, normalize liver enzymes, reduce hepatic inflammation, and lower the risks of progressive fibrosis, cirrhosis, end-stage liver failure, and hepatocellular carcinoma.