They function by binding to intracellular progesterone receptors, thereby suppressing gonadotropin release, suppressing ovulation, thickening cervical mucus, and inhibiting estrogen-driven endometrial proliferation.

Clinically, progestins are widely utilized for contraception, the management of abnormal uterine bleeding, endometriosis, and secondary amenorrhea, as well as to prevent endometrial hyperplasia and malignancy in individuals with an intact uterus undergoing menopausal estrogen therapy.

Select agents are also indicated in oncology, including the palliative treatment of advanced hormone-dependent endometrial or breast cancers.

drugs.com
Progestins are synthetic progestogens engineered to replicate the biological activity of endogenous progesterone
nih.gov
Progestins are synthetic progestogens engineered to replicate the biological activity of endogenous progesterone
drugbank.com
They function by binding to intracellular progesterone receptors, thereby suppressing gonadotropin release, suppressing ovulation, thickening cervical mucus, and inhibiting estrogen-driven endometrial proliferation Select agents are also indicated in oncology, including the palliative treatment of advanced hormone-dependent endometrial or breast cancers
nih.gov
They function by binding to intracellular progesterone receptors, thereby suppressing gonadotropin release, suppressing ovulation, thickening cervical mucus, and inhibiting estrogen-driven endometrial proliferation
cancer.gov
They function by binding to intracellular progesterone receptors, thereby suppressing gonadotropin release, suppressing ovulation, thickening cervical mucus, and inhibiting estrogen-driven endometrial proliferation
fda.gov
Clinically, progestins are widely utilized for contraception, the management of abnormal uterine bleeding, endometriosis, and secondary amenorrhea, as well as to prevent endometrial hyperplasia and malignancy in individuals with an intact uterus undergoing menopausal estrogen therapy
fda.gov
Clinically, progestins are widely utilized for contraception, the management of abnormal uterine bleeding, endometriosis, and secondary amenorrhea, as well as to prevent endometrial hyperplasia and malignancy in individuals with an intact uterus undergoing menopausal estrogen therapy
nih.gov
Clinically, progestins are widely utilized for contraception, the management of abnormal uterine bleeding, endometriosis, and secondary amenorrhea, as well as to prevent endometrial hyperplasia and malignancy in individuals with an intact uterus undergoing menopausal estrogen therapy
clevelandclinic.org
Select agents are also indicated in oncology, including the palliative treatment of advanced hormone-dependent endometrial or breast cancers
nih.gov
Select agents are also indicated in oncology, including the palliative treatment of advanced hormone-dependent endometrial or breast cancers

Progestins

Drugs in Progestins

About Progestins.