Drug class

Purine Analogues

Purine analogues are a class of antimetabolite medications chemically structured to mimic endogenous purine nucleosides and bases, such as adenine and guanine. Read more about Purine Analogues

75 drugs in this class 47 manufacturers

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Drugs in Purine Analogues

Showing 1–9 of 75 drugs

AZATHIOPRINE

PURINE ANALOGUES · RHEUMATOID ARTHRITIS ·+1
ZYDUS PHARMACEU

MERCAPTOPURINE

PURINE ANALOGUES · ACUTE LYMPHOID LEUKEMIA
Mylan Pharmaceuticals

CLADRIBINE

PURINE ANALOGUES · HAIRY CELL LEUKEMIA
MYLAN INSTITUTI

MERCAPTOPURINE

PURINE ANALOGUES · ACUTE LYMPHOID LEUKEMIA
ROXANE/WEST-WAR

CLADRIBINE

PURINE ANALOGUES · HAIRY CELL LEUKEMIA
APP/FRESENIUS K
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About Purine Analogues.

Purine analogues are a class of antimetabolite medications chemically structured to mimic endogenous purine nucleosides and bases, such as adenine and guanine.

Once incorporated into target cells and metabolically activated, they disrupt cellular proliferation by competing with natural substrates, inhibiting key enzymes in purine biosynthesis and DNA replication, and causing DNA strand termination or damage.

Therapeutically, these agents are primarily indicated for the treatment of hematologic malignancies, including acute leukemias, chronic lymphocytic leukemia, and hairy cell leukemia, as well as selected autoimmune conditions like multiple sclerosis and inflammatory bowel disease.