Retinoids and Derivatives (Systemic)

Retinoids and derivatives (systemic) comprise an oral or parenteral therapeutic class of natural and synthetic compounds chemically or functionally related to vitamin A

Retinoids and derivatives (systemic) comprise an oral or parenteral therapeutic class of natural and synthetic compounds chemically or functionally related to vitamin A These agents act as nuclear transcription modulators by binding to specific nuclear receptor families—primarily retinoic acid receptors (RAR) and retinoid X receptors (RXR)—to regulate gene expression governing cellular differentiation, proliferation, apoptosis, and immune activity

These agents act as nuclear transcription modulators by binding to specific nuclear receptor families—primarily retinoic acid receptors (RAR) and retinoid X receptors (RXR)—to regulate gene expression governing cellular differentiation, proliferation, apoptosis, and immune activity Systemically administered agents in this class are utilized predominantly in dermatology for severe, recalcitrant disorders of keratinization, such as severe nodulocystic acne and plaque psoriasis, as well as in oncol...

Systemically administered agents in this class are utilized predominantly in dermatology for severe, recalcitrant disorders of keratinization, such as severe nodulocystic acne and plaque psoriasis, as well as in oncology for conditions including cutaneous T-cell lymphoma and acute promyelocytic leukemia

Systemically administered agents in this class are utilized predominantly in dermatology for severe, recalcitrant disorders of keratinization, such as severe nodulocystic acne and plaque psoriasis, as well as in oncology for conditions including cutaneous T-cell lymphoma and acute promyelocytic leukemia