Drug class
Thalidomide and Derivative Immunomodulators
Thalidomide and derivative immunomodulators, commonly referred to as immunomodulatory drugs (IMiDs), are a distinct class of synthetic oral compounds that modify immune system activity, inhibit angiogenesis, and exert direct antiproliferative and cytotoxic effects against malignant cells. Read more about Thalidomide and Derivative Immunomodulators
30 drugs in this class 21 manufacturers
Drugs in Thalidomide and Derivative Immunomodulators
LENALIDOMIDE
LENALIDOMIDE
LENALIDOMIDE
LENALIDOMIDE
LENALIDOMIDE
LENALIDOMIDE
LENALIDOMIDE
LENALIDOMIDE
Thalidomide and derivative immunomodulators, commonly referred to as immunomodulatory drugs (IMiDs), are a distinct class of synthetic oral compounds that modify immune system activity, inhibit angiogenesis, and exert direct antiproliferative and cytotoxic effects against malignant cells.
These agents, which include thalidomide and its analogues lenalidomide and pomalidomide, primarily function by binding the E3 ubiquitin ligase component cereblon (CRBN), prompting the targeted ubiquitination and proteasomal degradation of critical lymphoid transcription factors.
Therapeutically, this drug class is predominantly employed in hematologic oncology to treat multiple myeloma and myelodysplastic syndromes, as well as in dermatologic manifestations of inflammatory conditions such as erythema nodosum leprosum.
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brainkart.com
Thalidomide and derivative immunomodulators, commonly referred to as immunomodulatory drugs (IMiDs), are a distinct class of synthetic oral compounds that modify immune system activity, inhibit angiogenesis, and exert direct antiproliferative and cytotoxic effects against malignant cells Therapeutically, this drug class is predominantly employed in hematologic oncology to treat multiple myeloma and myelodysplastic syndromes, as well as in dermatologic manifestations of inflammatory conditions su...
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nih.gov
Thalidomide and derivative immunomodulators, commonly referred to as immunomodulatory drugs (IMiDs), are a distinct class of synthetic oral compounds that modify immune system activity, inhibit angiogenesis, and exert direct antiproliferative and cytotoxic effects against malignant cells
-
nih.gov
These agents, which include thalidomide and its analogues lenalidomide and pomalidomide, primarily function by binding the E3 ubiquitin ligase component cereblon (CRBN), prompting the targeted ubiquitination and proteasomal degradation of critical lymphoid transcription factors
-
nih.gov
These agents, which include thalidomide and its analogues lenalidomide and pomalidomide, primarily function by binding the E3 ubiquitin ligase component cereblon (CRBN), prompting the targeted ubiquitination and proteasomal degradation of critical lymphoid transcription factors
-
nih.gov
These agents, which include thalidomide and its analogues lenalidomide and pomalidomide, primarily function by binding the E3 ubiquitin ligase component cereblon (CRBN), prompting the targeted ubiquitination and proteasomal degradation of critical lymphoid transcription factors
-
nih.gov
Therapeutically, this drug class is predominantly employed in hematologic oncology to treat multiple myeloma and myelodysplastic syndromes, as well as in dermatologic manifestations of inflammatory conditions such as erythema nodosum leprosum
-
jddonline.com
Therapeutically, this drug class is predominantly employed in hematologic oncology to treat multiple myeloma and myelodysplastic syndromes, as well as in dermatologic manifestations of inflammatory conditions such as erythema nodosum leprosum
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