Thrombopoietic Growth Factors

Thrombopoietic growth factors are a class of hematopoietic agents—including recombinant cytokines such as interleukin-11 (oprelvekin) and thrombopoietin receptor agonists—that promote megakaryocytopoiesis and accelerate platelet production By directly activating cell-surface receptors on hematopoietic stem cells and megakaryocyte progenitors, these agents stimulate progenitor proliferation and maturation into platelets to elevate peripheral platelet counts

Thrombopoietic growth factors are a class of hematopoietic agents—including recombinant cytokines such as interleukin-11 (oprelvekin) and thrombopoietin receptor agonists—that promote megakaryocytopoiesis and accelerate platelet production Therapeutically, they are utilized to manage or prevent clinically significant thrombocytopenia, most notably chemotherapy-induced thrombocytopenia in oncology

Therapeutically, they are utilized to manage or prevent clinically significant thrombocytopenia, most notably chemotherapy-induced thrombocytopenia in oncology