Topical Immunomodulator - Imidazoquinolinamines

Topical immunomodulators of the imidazoquinolinamine class, prototyped by imiquimod, are synthetic small-molecule immune response modifiers applied dermally to stimulate localized cell-mediated immunity

Topical immunomodulators of the imidazoquinolinamine class, prototyped by imiquimod, are synthetic small-molecule immune response modifiers applied dermally to stimulate localized cell-mediated immunity They act primarily as Toll-like receptor 7 agonists, triggering dendritic cells and macrophages to produce interferon-alpha and other proinflammatory cytokines that induce apoptosis of diseased cells and clear lesions

They act primarily as Toll-like receptor 7 agonists, triggering dendritic cells and macrophages to produce interferon-alpha and other proinflammatory cytokines that induce apoptosis of diseased cells and clear lesions

Clinically, these agents are utilized in dermatologic conditions, including external genital and perianal warts caused by human papillomavirus, actinic keratosis, and superficial basal cell carcinoma

Clinically, these agents are utilized in dermatologic conditions, including external genital and perianal warts caused by human papillomavirus, actinic keratosis, and superficial basal cell carcinoma