Drug class

Xanthines

Xanthines, also known as methylxanthines, are a therapeutic drug class consisting of purine-derived compounds that include agents such as theophylline, aminophylline, and caffeine. Read more about Xanthines

225 drugs in this class 111 manufacturers

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Drugs in Xanthines

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About Xanthines.

Xanthines, also known as methylxanthines, are a therapeutic drug class consisting of purine-derived compounds that include agents such as theophylline, aminophylline, and caffeine.

They primarily exert their pharmacological effects through nonselective inhibition of phosphodiesterase enzymes, which raises intracellular cyclic adenosine monophosphate levels to promote smooth muscle relaxation, alongside nonselective adenosine receptor antagonism and central nervous system stimulation.

Clinically, members of this class are utilized as bronchodilators to alleviate airway obstruction and bronchospasm in chronic obstructive pulmonary disease and asthma, and as respiratory stimulants for the management of apnea of prematurity.