Khapzory (levoleucovorin)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Leucovorin calcium is the calcium salt of folinic acid, an active metabolite of folic acid.
USES: This medication is used to treat or prevent serious blood cell disorders (such as thrombocytopenia, neutropenia, anemia) caused by certain drugs (folic acid antagonists such as methotrexate, trimethoprim, pyrimethamine). Some brands may also be used with a certain cancer drug (5-fluorouracil) to treat patients with colon cancer.
Generic name: levoleucovorin
Pronunciation: (LEE-voe-LOO-koe-VOR-in)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Khapzory
Indications
The following indications are listed for Khapzory:
- Adjunct To Fluorouracil Treatment Of Colorectal Cancer
- Bone Marrow Suppression Due To Folic Acid Antagonism
- Methotrexate Toxicity
- Pyrimethamine Toxicity
- Sulfadiazine Toxicity
- Trimethoprim Toxicity
- Trimetrexate Toxicity
Also known as: Adjunct To Fluorouracil Treatment Of Adenocarcinoma Of Colon And Rectum, Adjuvant Therapy With 5-Fu For Colorectal Cancer, Bone Marrow Depression Due To Folic Acid Antagonism, Bone Marrow Hypoplasia Due To Folic Acid Antagonism, Hypoplasia Of Bone Marrow Due To Folic Acid Antagonism, Mtx Toxicity, Myelosuppression Due To Folic Acid Antagonism, Tmp Toxicity.
Dosing
Dosage of leucovorin calcium is expressed in terms of leucovorin.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies have not been performed with leucovorin. It is also not known whether leucovorin can cause fetal harm when administered to pregnant women. Leucovorin should be used during pregnancy only when clearly needed.
Since it is not known if leucovorin is distributed into milk, the drug should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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