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Trifluoperazine Hcl (trifluoperazine HCl)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Trifluoperazine hydrochloride is a phenothiazine antipsychotic agent.

USES: This medication is used to treat certain mental/mood disorders (such as schizophrenia, psychotic disorders). Trifluoperazine belongs to a class of drugs known as antipsychotics. It works by helping to restore the balance of certain natural substances in the brain.

Generic name: trifluoperazine HCl
Pronunciation: (TRYE-floo-oh-PER-a-zeen)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

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Indications

The following indications are listed for Trifluoperazine Hcl:

  • Anxiety
  • Schizophrenia

Also known as: Dementia Praecox, Parergasia.

Dosing

Dosage of trifluoperazine hydrochloride is expressed in terms of trifluoperazine. Dosage must be carefully adjusted according to individual requirements and response, using the lowest possible effective dosage. Dosage should be increased more gradually in debilitated, emaciated, or geriatric patients. Since geriatric patients may be more susceptible to hypotension and neuromuscular reactions, these patients should be observed closely; in general, dosages in the lower end of the range are sufficient for most geriatric patients. Because of the long duration of action of trifluoperazine, patients may be controlled with twice-daily dosing; in some patients, once-daily dosing may be adequate. Optimum therapeutic response usually occurs within 2-3 weeks. After the maximum response is attained, dosage should be reduced gradually to the minimum effective level for maintenance. Because of the risk of adverse reactions associated with cumulative effects of phenothiazines, patients with a history of long-term therapy with trifluoperazine and/or other antipsychotic agents should be evaluated periodically to determine whether maintenance dosage could be decreased or drug therapy discontinued.

Drug interactions

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Contraindications

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Adverse reactions

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Precautions

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ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data