Indication
Acquired factor VIII deficiency disease
Acquired factor VIII deficiency disease, also known as acquired hemophilia A, is a rare autoimmune bleeding disorder characterized by the spontaneous development of neutralizing autoantibodies directed against endogenous coagulation factor VIII. Read more about Acquired factor VIII deficiency disease
7 drugs 5 manufacturers
Drugs that treat it
Common Acquired factor VIII deficiency disease therapies.
WILATE (antihemophilic factor, human/von Willebrand factor,human)
HUMATE-P (antihemophilic factor, human/von Willebrand factor,human)
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Coming soonAcquired factor VIII deficiency disease, also known as acquired hemophilia A, is a rare autoimmune bleeding disorder characterized by the spontaneous development of neutralizing autoantibodies directed against endogenous coagulation factor VIII.
This condition affects the hematologic and vascular systems in individuals without a personal or hereditary history of coagulopathy, occurring most frequently in older adults of either sex and occasionally in the postpartum setting or in association with underlying autoimmune diseases or malignancies.
Pathophysiologically, the antibody-mediated neutralization or clearance of factor VIII disrupts the intrinsic coagulation pathway, manifesting clinically as sudden, often severe or life-threatening mucocutaneous hemorrhage, extensive subcutaneous ecchymoses, deep soft-tissue or intramuscular hematomas, and prolonged activated partial thromboplastin time that fails to correct with normal plasma.
- nih.gov
Acquired factor VIII deficiency disease, also known as acquired hemophilia A, is a rare autoimmune bleeding disorder characterized by the spontaneous development of neutralizing autoantibodies directed against endogenous coagulation factor VIII
- nih.gov
Acquired factor VIII deficiency disease, also known as acquired hemophilia A, is a rare autoimmune bleeding disorder characterized by the spontaneous development of neutralizing autoantibodies directed against endogenous coagulation factor VIII
- nih.gov
This condition affects the hematologic and vascular systems in individuals without a personal or hereditary history of coagulopathy, occurring most frequently in older adults of either sex and occasionally in the postpartum setting or in association with underlying autoimmune diseases or malignancies Pathophysiologically, the antibody-mediated neutralization or clearance of factor VIII disrupts the intrinsic coagulation pathway, manifesting clinically as sudden, often severe or life-threatening ...
- nih.gov
This condition affects the hematologic and vascular systems in individuals without a personal or hereditary history of coagulopathy, occurring most frequently in older adults of either sex and occasionally in the postpartum setting or in association with underlying autoimmune diseases or malignancies Pathophysiologically, the antibody-mediated neutralization or clearance of factor VIII disrupts the intrinsic coagulation pathway, manifesting clinically as sudden, often severe or life-threatening ...
- haemophilia.org.au
This condition affects the hematologic and vascular systems in individuals without a personal or hereditary history of coagulopathy, occurring most frequently in older adults of either sex and occasionally in the postpartum setting or in association with underlying autoimmune diseases or malignancies
- nih.gov
Pathophysiologically, the antibody-mediated neutralization or clearance of factor VIII disrupts the intrinsic coagulation pathway, manifesting clinically as sudden, often severe or life-threatening mucocutaneous hemorrhage, extensive subcutaneous ecchymoses, deep soft-tissue or intramuscular hematomas, and prolonged activated partial thromboplastin time that fails to correct with normal plasma
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