Actinomycosis

Actinomycosis is a rare, subacute to chronic, slowly progressive bacterial infection primarily caused by anaerobic or microaerophilic, filamentous, Gram-positive species of the genus *Actinomyces*, most notably *Actinomyces israelii* Pathophysiologically, it is characterized by contiguous tissue invasion that disregards tissue planes, producing indurated granulomatous lesions, extensive fibrosis, multiple abscesses, and draining sinus tracts that classically extrude macroscopic macroscopic bacte...

Actinomycosis is a rare, subacute to chronic, slowly progressive bacterial infection primarily caused by anaerobic or microaerophilic, filamentous, Gram-positive species of the genus *Actinomyces*, most notably *Actinomyces israelii* Typically an endogenous infection triggered by mucosal barrier disruption from trauma, dental disease, surgery, or foreign bodies, it most commonly affects the cervicofacial region, though thoracic, abdominopelvic, and central nervous system involvement can also occ...

Typically an endogenous infection triggered by mucosal barrier disruption from trauma, dental disease, surgery, or foreign bodies, it most commonly affects the cervicofacial region, though thoracic, abdominopelvic, and central nervous system involvement can also occur Pathophysiologically, it is characterized by contiguous tissue invasion that disregards tissue planes, producing indurated granulomatous lesions, extensive fibrosis, multiple abscesses, and draining sinus tracts that classically ex...

Typically an endogenous infection triggered by mucosal barrier disruption from trauma, dental disease, surgery, or foreign bodies, it most commonly affects the cervicofacial region, though thoracic, abdominopelvic, and central nervous system involvement can also occur