Acute gonococcal urethritis

Acute gonococcal urethritis is an acute, sexually transmitted mucosal infection of the lower urinary tract caused by the Gram-negative diplococcus *Neisseria gonorrhoeae* Pathophysiologically, the bacteria adhere to and invade columnar epithelial cells, inciting an intense, localized polymorphonuclear leukocyte response This inflammatory cascade clinically defines the condition through sudden-onset dysuria and copious, profuse purulent or mucopurulent urethral discharge

It predominantly affects sexually active adolescents and adults, manifesting most prominently in men as acute inflammation of the urethral mucosa

It predominantly affects sexually active adolescents and adults, manifesting most prominently in men as acute inflammation of the urethral mucosa

Pathophysiologically, the bacteria adhere to and invade columnar epithelial cells, inciting an intense, localized polymorphonuclear leukocyte response

This inflammatory cascade clinically defines the condition through sudden-onset dysuria and copious, profuse purulent or mucopurulent urethral discharge