Allergic bronchopulmonary aspergillosis

Allergic bronchopulmonary aspergillosis is a complex immunological pulmonary disorder characterized by a hypersensitivity response to colonization of the lower airways by *Aspergillus* species, primarily *Aspergillus fumigatus* It predominantly affects individuals with underlying chronic respiratory conditions, specifically asthma and cystic fibrosis

Allergic bronchopulmonary aspergillosis is a complex immunological pulmonary disorder characterized by a hypersensitivity response to colonization of the lower airways by *Aspergillus* species, primarily *Aspergillus fumigatus*

It predominantly affects individuals with underlying chronic respiratory conditions, specifically asthma and cystic fibrosis Pathophysiologically driven by an exaggerated T-helper type 2 inflammatory reaction, the condition is clinically marked by recurrent wheezing, cough with brown mucus plugs, pulmonary infiltrates, peripheral blood and sputum eosinophilia, and elevated total and fungus-specific serum immunoglobulin E levels

Pathophysiologically driven by an exaggerated T-helper type 2 inflammatory reaction, the condition is clinically marked by recurrent wheezing, cough with brown mucus plugs, pulmonary infiltrates, peripheral blood and sputum eosinophilia, and elevated total and fungus-specific serum immunoglobulin E levels Without timely recognition, persistent airway inflammation can cause central bronchiectasis and irreversible fibrotic lung damage