Allergic dermatitis

Allergic dermatitis is an inflammatory skin condition triggered by an immunologically mediated hypersensitivity reaction following cutaneous contact with, or systemic exposure to, an offending allergen

Allergic dermatitis is an inflammatory skin condition triggered by an immunologically mediated hypersensitivity reaction following cutaneous contact with, or systemic exposure to, an offending allergen Affecting pediatric and adult populations across all demographics, it primarily impacts the integumentary system, classically manifesting as a cell-mediated, type IV delayed hypersensitivity response following prior sensitization

Affecting pediatric and adult populations across all demographics, it primarily impacts the integumentary system, classically manifesting as a cell-mediated, type IV delayed hypersensitivity response following prior sensitization Upon re-exposure, allergen-specific T lymphocytes trigger localized cutaneous inflammation characterized histologically by epidermal spongiosis and dermal perivascular infiltration

Upon re-exposure, allergen-specific T lymphocytes trigger localized cutaneous inflammation characterized histologically by epidermal spongiosis and dermal perivascular infiltration

Clinically, acute presentations feature intense pruritus, erythema, edema, and vesiculation, which can progress in chronic stages to scaling, lichenification, and painful fissuring

Clinically, acute presentations feature intense pruritus, erythema, edema, and vesiculation, which can progress in chronic stages to scaling, lichenification, and painful fissuring