Indication

Androgen deficiency

Androgen deficiency is an endocrine disorder characterized by insufficient production or action of male sex steroid hormones, predominantly testosterone. Read more about Androgen deficiency

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About Androgen deficiency.

Androgen deficiency is an endocrine disorder characterized by insufficient production or action of male sex steroid hormones, predominantly testosterone.

The condition primarily impacts the male reproductive and musculoskeletal systems, arising from intrinsic testicular failure (primary hypogonadism) or hypothalamic-pituitary axis dysfunction (secondary hypogonadism).

Clinical features include decreased libido, erectile dysfunction, oligospermia or azoospermia, loss of lean muscle mass, reduced bone mineral density, fatigue, and vasomotor symptoms, confirmed biochemically by consistently subnormal serum testosterone concentrations.

While less commonly defined as a clinical indication in females, androgen deficiency can also occur in women secondary to bilateral oophorectomy, adrenal insufficiency, or hypopituitarism.

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