Indication

Atrophic vaginitis associated with menopause

Atrophic vaginitis associated with menopause is a chronic, hypoestrogenic inflammatory disorder of the female genitourinary tract, representing a core vaginal component of the broader genitourinary syndrome of menopause. Read more about Atrophic vaginitis associated with menopause

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About Atrophic vaginitis associated with menopause.

Atrophic vaginitis associated with menopause is a chronic, hypoestrogenic inflammatory disorder of the female genitourinary tract, representing a core vaginal component of the broader genitourinary syndrome of menopause.

Arising from the natural or surgically induced decline in circulating ovarian estrogens during and after the menopausal transition, the condition affects peri- and postmenopausal women.

Pathophysiologically, estrogen deprivation causes thinning of the stratified squamous epithelium, loss of vaginal rugae and elasticity, reduced vascular perfusion, and decreased glandular secretions.

These structural alterations lead to an elevated vaginal pH, depletion of protective lactobacilli, and secondary mucosal inflammation, which clinically manifest as persistent vaginal dryness, burning, pruritus, leukorrhea, postcoital spotting, and dyspareunia.

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