B. fragilis infection

A *B. fragilis* infection is an opportunistic, often polymicrobial bacterial infection caused by *Bacteroides fragilis*, an obligate anaerobic, gram-negative bacillus that normally resides as a commensal organism within the human gastrointestinal tract Clinically significant infection arises when mucosal barriers are disrupted by abdominal trauma, gastrointestinal perforation, bowel ischemia, surgery, or underlying pelvic and intestinal disease, allowing the organism to invade normally sterile a...

A *B. fragilis* infection is an opportunistic, often polymicrobial bacterial infection caused by *Bacteroides fragilis*, an obligate anaerobic, gram-negative bacillus that normally resides as a commensal organism within the human gastrointestinal tract Clinically significant infection arises when mucosal barriers are disrupted by abdominal trauma, gastrointestinal perforation, bowel ischemia, surgery, or underlying pelvic and intestinal disease, allowing the organism to invade normally sterile a...

Clinically significant infection arises when mucosal barriers are disrupted by abdominal trauma, gastrointestinal perforation, bowel ischemia, surgery, or underlying pelvic and intestinal disease, allowing the organism to invade normally sterile anatomical sites The condition predominantly manifests in adults and postoperative surgical patients as localized intra-abdominal or pelvic abscesses, peritonitis, complicated skin and soft tissue infections, or life-threatening bacteremia

The condition predominantly manifests in adults and postoperative surgical patients as localized intra-abdominal or pelvic abscesses, peritonitis, complicated skin and soft tissue infections, or life-threatening bacteremia

The condition predominantly manifests in adults and postoperative surgical patients as localized intra-abdominal or pelvic abscesses, peritonitis, complicated skin and soft tissue infections, or life-threatening bacteremia

Pathophysiologically, the organism's distinctive capsular polysaccharide complex drives purulent inflammation and potent intra-abdominal abscess formation while protecting the bacteria from host phagocytosis and complement-mediated killing