Indication

Bleeding episode in acquired factor VIII deficiency disease

A bleeding episode in acquired factor VIII deficiency disease—commonly known as acquired hemophilia A—is an acute hemorrhagic event arising from a rare autoimmune disorder of the coagulation cascade. Read more about Bleeding episode in acquired factor VIII deficiency disease

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HUMATE-P (antihemophilic factor, human/von Willebrand factor,human)

ANTIHEMOPHILIC PRODUCTS·HEMOPHILIA A·+6

CSL Behring

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About Bleeding episode in acquired factor VIII deficiency disease.

Pathophysiologically, the condition is driven by the development of neutralizing autoantibodies (inhibitors) against endogenous clotting factor VIII, which severely disrupts the intrinsic pathway of secondary hemostasis.

This disorder primarily manifests in older adults of either sex and during the postpartum period, often without a personal or family history of bleeding diatheses.

Clinically, these bleeding episodes characteristically present with extensive subcutaneous ecchymoses, deep intramuscular or retroperitoneal hematomas, mucosal hemorrhage, or gastrointestinal bleeding that can be severe and life-threatening.

nih.gov
A bleeding episode in acquired factor VIII deficiency disease—commonly known as acquired hemophilia A—is an acute hemorrhagic event arising from a rare autoimmune disorder of the coagulation cascade Pathophysiologically, the condition is driven by the development of neutralizing autoantibodies (inhibitors) against endogenous clotting factor VIII, which severely disrupts the intrinsic pathway of secondary hemostasis Clinically, these bleeding episodes characteristically present with extensive sub...
nih.gov
A bleeding episode in acquired factor VIII deficiency disease—commonly known as acquired hemophilia A—is an acute hemorrhagic event arising from a rare autoimmune disorder of the coagulation cascade
nih.gov
Pathophysiologically, the condition is driven by the development of neutralizing autoantibodies (inhibitors) against endogenous clotting factor VIII, which severely disrupts the intrinsic pathway of secondary hemostasis
haematologica.org
Pathophysiologically, the condition is driven by the development of neutralizing autoantibodies (inhibitors) against endogenous clotting factor VIII, which severely disrupts the intrinsic pathway of secondary hemostasis This disorder primarily manifests in older adults of either sex and during the postpartum period, often without a personal or family history of bleeding diatheses
mdpi.com
This disorder primarily manifests in older adults of either sex and during the postpartum period, often without a personal or family history of bleeding diatheses
unc.edu
This disorder primarily manifests in older adults of either sex and during the postpartum period, often without a personal or family history of bleeding diatheses
ashpublications.org
Clinically, these bleeding episodes characteristically present with extensive subcutaneous ecchymoses, deep intramuscular or retroperitoneal hematomas, mucosal hemorrhage, or gastrointestinal bleeding that can be severe and life-threatening
rarediseases.org
Clinically, these bleeding episodes characteristically present with extensive subcutaneous ecchymoses, deep intramuscular or retroperitoneal hematomas, mucosal hemorrhage, or gastrointestinal bleeding that can be severe and life-threatening

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