Cardiogenic shock

Cardiogenic shock is a critical, life-threatening cardiovascular syndrome characterized by primary cardiac pump failure that leads to severely reduced cardiac output, systemic hypoperfusion, and widespread tissue hypoxia despite adequate intravascular volume Most commonly triggered by acute myocardial infarction, it can also stem from severe cardiomyopathies, valvular disruption, mechanical complications, or intractable arrhythmias Clinically, it manifests as profound arterial hypotension, alter...

Cardiogenic shock is a critical, life-threatening cardiovascular syndrome characterized by primary cardiac pump failure that leads to severely reduced cardiac output, systemic hypoperfusion, and widespread tissue hypoxia despite adequate intravascular volume Most commonly triggered by acute myocardial infarction, it can also stem from severe cardiomyopathies, valvular disruption, mechanical complications, or intractable arrhythmias

Pathophysiologically, sustained myocardial dysfunction initiates a vicious cycle of persistent hypotension, increased ventricular filling pressures, systemic vasoconstriction, and impaired coronary perfusion

Pathophysiologically, sustained myocardial dysfunction initiates a vicious cycle of persistent hypotension, increased ventricular filling pressures, systemic vasoconstriction, and impaired coronary perfusion

Clinically, it manifests as profound arterial hypotension, altered mental status, cold extremities, oliguria, elevated serum lactate, and progressive multiorgan dysfunction