Indication

Central retinal vein occlusion with macular edema

Central retinal vein occlusion with macular edema is a vision-threatening ophthalmic disorder characterized by fluid accumulation in the central retina following thrombus formation or obstruction within the primary outflow vein at or near the lamina cribrosa. Read more about Central retinal vein occlusion with macular edema

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Common Central retinal vein occlusion with macular edema therapies.

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EYLEA HD (aflibercept)

OPHTHALMIC - MACULAR DEGENERATION AGENTS·DIABETIC RETINOPATHY·+3
Regeneron Pharmaceuticals, Inc.
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About Central retinal vein occlusion with macular edema.

Central retinal vein occlusion with macular edema is a vision-threatening ophthalmic disorder characterized by fluid accumulation in the central retina following thrombus formation or obstruction within the primary outflow vein at or near the lamina cribrosa.

It most commonly affects older adults and individuals with underlying systemic vascular comorbidities, including hypertension, diabetes mellitus, and cardiovascular disease.

Venous occlusion leads to elevated intraluminal capillary pressure, retinal ischemia, and increased vascular permeability driven by the upregulation of vascular endothelial growth factor and inflammatory mediators.

Clinically, this results in widespread intraretinal hemorrhages across all four retinal quadrants, cystoid swelling of the macula, and sudden, painless loss or distortion of central vision.

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