Indication

Chloasma

Chloasma, commonly referred to as melasma or the "mask of pregnancy," is an acquired pigmentary disorder of the integumentary system characterized by symmetric, irregularly bordered, light-to-dark brown macules and patches. Read more about Chloasma

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About Chloasma.

Chloasma, commonly referred to as melasma or the "mask of pregnancy," is an acquired pigmentary disorder of the integumentary system characterized by symmetric, irregularly bordered, light-to-dark brown macules and patches.

It predominantly affects sun-exposed areas of the face, most frequently involving the forehead, cheeks, upper lip, and chin, with the highest prevalence seen in women of reproductive age, particularly during pregnancy, as well as individuals with darker skin phototypes.

Pathophysiologically, the condition is driven by localized melanocyte hyperactivity and accelerated melanogenesis, triggered predominantly by ultraviolet radiation, visible light, and hormonal fluctuations involving estrogen and progesterone.

Histologically, excess melanin is deposited within the epidermis, dermis, or both layers, often accompanied by dermal elastosis and increased vascularity.

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