Chronic lymphoid leukemia

Chronic lymphoid leukemia, more commonly termed chronic lymphocytic leukemia (CLL), is an indolent hematologic malignancy of the lymphatic and circulatory systems characterized by the clonal proliferation and progressive accumulation of mature-appearing but immunologically dysfunctional B lymphocytes Primarily affecting older adults, the abnormal cells infiltrate the bone marrow, peripheral blood, spleen, and lymph nodes Key clinical and pathophysiologic features include sustained monoclonal B-c...

Chronic lymphoid leukemia, more commonly termed chronic lymphocytic leukemia (CLL), is an indolent hematologic malignancy of the lymphatic and circulatory systems characterized by the clonal proliferation and progressive accumulation of mature-appearing but immunologically dysfunctional B lymphocytes

Primarily affecting older adults, the abnormal cells infiltrate the bone marrow, peripheral blood, spleen, and lymph nodes

Key clinical and pathophysiologic features include sustained monoclonal B-cell lymphocytosis, generalized lymphadenopathy, splenomegaly, and progressive bone marrow failure leading to anemia, thrombocytopenia, and increased susceptibility to infections

Key clinical and pathophysiologic features include sustained monoclonal B-cell lymphocytosis, generalized lymphadenopathy, splenomegaly, and progressive bone marrow failure leading to anemia, thrombocytopenia, and increased susceptibility to infections