Indication

Citrobacter urinary tract infection

A Citrobacter urinary tract infection is a localized or systemic bacterial infection of the urinary tract caused by opportunistic, Gram-negative bacilli of the genus *Citrobacter*, most commonly *Citrobacter freundii* or *Citrobacter koseri*. Read more about Citrobacter urinary tract infection

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AZTREONAM

SEPSIS CAUSED BY ENTEROBACTER·+57
APP/PREMIERPRO
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About Citrobacter urinary tract infection.

A Citrobacter urinary tract infection is a localized or systemic bacterial infection of the urinary tract caused by opportunistic, Gram-negative bacilli of the genus *Citrobacter*, most commonly *Citrobacter freundii* or *Citrobacter koseri*.

Primarily manifesting as a healthcare-associated or complicated infection, it predominantly affects hospitalized, elderly, or immunocompromised individuals, as well as patients with urinary catheterization, structural anomalies, or prior broad-spectrum antibiotic exposure.

Clinical features range from lower urinary tract symptoms, such as dysuria, urgency, and frequency, to upper urinary tract involvement marked by flank pain, fever, and leukocyturia, with potential progression to bacteremia or pyelonephritis.

Pathophysiologically, the organism ascends into the urinary collecting system, where its ability to form biofilms and express inducible beta-lactamases frequently contributes to persistence and multidrug resistance.

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