Clonorchiasis due to C. sinensis

Clonorchiasis due to *Clonorchis sinensis* is a foodborne parasitic infection caused by ingestion of raw, pickled, or undercooked freshwater fish containing the encysted larvae (metacercariae) of the Chinese or oriental liver fluke The ingested parasites excyst in the duodenum and migrate into the human hepatobiliary system, where adult flukes reside within the intrahepatic and medium-sized bile ducts

Clonorchiasis due to *Clonorchis sinensis* is a foodborne parasitic infection caused by ingestion of raw, pickled, or undercooked freshwater fish containing the encysted larvae (metacercariae) of the Chinese or oriental liver fluke The ingested parasites excyst in the duodenum and migrate into the human hepatobiliary system, where adult flukes reside within the intrahepatic and medium-sized bile ducts While many infections are asymptomatic, progressive or heavy infestations cause mechanical bile...

While many infections are asymptomatic, progressive or heavy infestations cause mechanical bile duct obstruction, chronic epithelial irritation, periductal inflammation, and fibrosis

Defining clinical manifestations include right upper quadrant abdominal pain, hepatomegaly, recurrent cholangitis, and cholelithiasis, with long-standing chronic infection serving as an established risk factor for cholangiocarcinoma

Defining clinical manifestations include right upper quadrant abdominal pain, hepatomegaly, recurrent cholangitis, and cholelithiasis, with long-standing chronic infection serving as an established risk factor for cholangiocarcinoma