Biltricide (praziquantel)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Praziquantel is a synthetic anthelmintic agent that is structurally unrelated to other currently available anthelmintic agents.
USES: This medication is used to treat infections of certain parasites (such as Schistosoma and liver flukes). Curing parasitic infections helps to improve your health and quality of life. Praziquantel belongs to a class of drugs known as anthelmintics.
It works by killing the parasites. It also paralyzes the parasites, causing them to release their hold on the blood vessel walls so the body can remove them naturally.
Generic name: praziquantel
Pronunciation: (prazz-ih-KWAN-tull)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Biltricide
Indications
The following indications are listed for Biltricide:
- Clonorchiasis Due To C. Sinensis
- Opisthorchiasis
- Schistosomiasis
Also known as: Bilharziasis, Bilharziosis, Blood Fluke Infection, Cat Liver Fluke Infection, Chinese Liver Fluke Disease, Clonorchiasis Due To Clonorchis Sinensis, Clonorchiosis, Hemic Distomiasis, Hepatic Distomiasis Due To Clonorchis Sinensis, Infection Due To Schistosomes, Opisthorciosis, Oriental Liver Fluke Disease, Snail Fever.
Dosing
Dosage adjustments are not necessary in patients with renal impairment.
Praziquantel is administered orally. The tablets should not be chewed but can be halved or quartered to allow administration of individualized doses. Patients should be instructed to immediately swallow the praziquantel tablets, halves, and/or quarters with a sufficient amount of water during meals. Retention of the tablets or tablet segments in the mouth may cause gagging or vomiting as a result of the drug's bitter taste. Some clinicians state that regurgitation during administration of the tablets may theoretically predispose the patient to the development of cysticercosis during therapy for Taenia solium+ infections.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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Reproduction studies in rats and rabbits using praziquantel dosages up to 40 times the usual human dosage have not revealed evidence of harm to the fetus. An increase in the rate of spontaneous abortion occurred in rats following administration of praziquantel dosages 3 times the usual human dosage. There are no adequate and controlled studies to date using praziquantel in pregnant women, and the drug should be used during pregnancy only when clearly needed.
Since praziquantel is distributed into milk, women should temporarily discontinue nursing on the day of praziquantel therapy and for 72 hours after administration of the last dose of the drug.
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ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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