Schistosomiasis

Schistosomiasis is an acute and chronic parasitic intravascular infection caused by trematode blood flukes of the genus *Schistosoma*, primarily *Schistosoma mansoni*, *S. haematobium*, and *S. japonicum* Humans contract the disease when larval cercariae released from freshwater snail intermediate hosts penetrate intact skin during contact with contaminated fresh water Adult worms inhabit the mesenteric or vesical venules, where deposition of hundreds to thousands of eggs per day triggers host g...

Humans contract the disease when larval cercariae released from freshwater snail intermediate hosts penetrate intact skin during contact with contaminated fresh water

Adult worms inhabit the mesenteric or vesical venules, where deposition of hundreds to thousands of eggs per day triggers host granulomatous inflammatory reactions and tissue fibrosis

Adult worms inhabit the mesenteric or vesical venules, where deposition of hundreds to thousands of eggs per day triggers host granulomatous inflammatory reactions and tissue fibrosis Clinical manifestations range from acute Katayama syndrome to organ-specific chronic disease, presenting as hepatic periportal fibrosis and portal hypertension in intestinal schistosomiasis, or hematuria, bladder wall fibrosis, and obstructive uropathy in urogenital schistosomiasis

Clinical manifestations range from acute Katayama syndrome to organ-specific chronic disease, presenting as hepatic periportal fibrosis and portal hypertension in intestinal schistosomiasis, or hematuria, bladder wall fibrosis, and obstructive uropathy in urogenital schistosomiasis

Clinical manifestations range from acute Katayama syndrome to organ-specific chronic disease, presenting as hepatic periportal fibrosis and portal hypertension in intestinal schistosomiasis, or hematuria, bladder wall fibrosis, and obstructive uropathy in urogenital schistosomiasis