Complicated bacterial peritonitis

Complicated bacterial peritonitis is a severe, acute infection of the peritoneal membrane and peritoneal cavity characterized by extensive inflammation, systemic toxicity, and associated anatomical or physiological complications Pathophysiologically, microbial contamination—often by enteric gram-negative bacilli, enterococci, or polymicrobial flora—triggers widespread mesothelial inflammation, purulent exudate accumulation, and profound peritoneal barrier breakdown that can rapidly precipitate s...

Complicated bacterial peritonitis is a severe, acute infection of the peritoneal membrane and peritoneal cavity characterized by extensive inflammation, systemic toxicity, and associated anatomical or physiological complications

Complicated bacterial peritonitis is a severe, acute infection of the peritoneal membrane and peritoneal cavity characterized by extensive inflammation, systemic toxicity, and associated anatomical or physiological complications

Affecting the gastrointestinal and hepatobiliary systems, it typically arises either as secondary peritonitis resulting from gastrointestinal perforation, anastomotic leak, ischemia, or intra-abdominal abscess formation, or as high-risk spontaneous bacterial peritonitis complicated by acute kidney injury, hepatic encephalopathy, sepsis, or treatment-refractory loculations

Affecting the gastrointestinal and hepatobiliary systems, it typically arises either as secondary peritonitis resulting from gastrointestinal perforation, anastomotic leak, ischemia, or intra-abdominal abscess formation, or as high-risk spontaneous bacterial peritonitis complicated by acute kidney injury, hepatic encephalopathy, sepsis, or treatment-refractory loculations

Pathophysiologically, microbial contamination—often by enteric gram-negative bacilli, enterococci, or polymicrobial flora—triggers widespread mesothelial inflammation, purulent exudate accumulation, and profound peritoneal barrier breakdown that can rapidly precipitate septic shock and multiorgan failure

Pathophysiologically, microbial contamination—often by enteric gram-negative bacilli, enterococci, or polymicrobial flora—triggers widespread mesothelial inflammation, purulent exudate accumulation, and profound peritoneal barrier breakdown that can rapidly precipitate septic shock and multiorgan failure