Diabetes mellitus

Diabetes mellitus is a chronic metabolic disorder affecting the endocrine and vascular systems, characterized by persistent hyperglycemia resulting from impaired insulin secretion, reduced insulin sensitivity, or both The condition encompasses heterogeneous etiologies—primarily absolute insulin deficiency due to autoimmune pancreatic beta-cell destruction or progressive relative insulin deficiency coupled with peripheral insulin resistance Over time, chronic hyperglycemia leads to widespread mic...

Diabetes mellitus is a chronic metabolic disorder affecting the endocrine and vascular systems, characterized by persistent hyperglycemia resulting from impaired insulin secretion, reduced insulin sensitivity, or both

The condition encompasses heterogeneous etiologies—primarily absolute insulin deficiency due to autoimmune pancreatic beta-cell destruction or progressive relative insulin deficiency coupled with peripheral insulin resistance

Clinically, it manifests with classic osmotic symptoms such as polyuria, polydipsia, and unexplained weight loss, alongside systemic metabolic disruptions

Clinically, it manifests with classic osmotic symptoms such as polyuria, polydipsia, and unexplained weight loss, alongside systemic metabolic disruptions