Diabetic retinopathy

Diabetic retinopathy is a chronic neurovascular complication of diabetes mellitus that affects the retinal vasculature of the eye and represents a leading cause of preventable vision impairment and blindness Prolonged systemic hyperglycemia induces biochemical stress and microvascular damage, leading to pericyte loss, basement membrane thickening, capillary occlusion, and breakdown of the blood-retinal barrier Clinically, the disease progresses from nonproliferative stages—characterized by micro...

Diabetic retinopathy is a chronic neurovascular complication of diabetes mellitus that affects the retinal vasculature of the eye and represents a leading cause of preventable vision impairment and blindness Clinically, the disease progresses from nonproliferative stages—characterized by microaneurysms, intraretinal hemorrhages, exudates, and macular edema—to proliferative diabetic retinopathy, defined by retinal ischemia-driven neovascularization that can cause vitreous hemorrhage, fibrovascula...

Diabetic retinopathy is a chronic neurovascular complication of diabetes mellitus that affects the retinal vasculature of the eye and represents a leading cause of preventable vision impairment and blindness

Prolonged systemic hyperglycemia induces biochemical stress and microvascular damage, leading to pericyte loss, basement membrane thickening, capillary occlusion, and breakdown of the blood-retinal barrier