Diphtheria carrier state

Diphtheria carrier state is an asymptomatic colonizing infection of the mucosal membranes of the upper respiratory tract—most commonly the nasopharynx—or, less frequently, the skin by *Corynebacterium diphtheriae* Individuals in this clinical state, whether fully immunized or convalescing from acute disease, harbor and shed the bacteria without manifesting classical toxigenic symptoms such as pharyngeal pseudomembrane formation, airway obstruction, or systemic cardioneurologic toxicity

Diphtheria carrier state is an asymptomatic colonizing infection of the mucosal membranes of the upper respiratory tract—most commonly the nasopharynx—or, less frequently, the skin by *Corynebacterium diphtheriae* Pathophysiologically, the organism colonizes superficial epithelial tissues, enabling persistent transmission to susceptible populations through respiratory droplets or direct exudative contact despite the presence of circulating host antitoxin antibodies

Diphtheria carrier state is an asymptomatic colonizing infection of the mucosal membranes of the upper respiratory tract—most commonly the nasopharynx—or, less frequently, the skin by *Corynebacterium diphtheriae* Individuals in this clinical state, whether fully immunized or convalescing from acute disease, harbor and shed the bacteria without manifesting classical toxigenic symptoms such as pharyngeal pseudomembrane formation, airway obstruction, or systemic cardioneurologic toxicity

Individuals in this clinical state, whether fully immunized or convalescing from acute disease, harbor and shed the bacteria without manifesting classical toxigenic symptoms such as pharyngeal pseudomembrane formation, airway obstruction, or systemic cardioneurologic toxicity Pathophysiologically, the organism colonizes superficial epithelial tissues, enabling persistent transmission to susceptible populations through respiratory droplets or direct exudative contact despite the presence of circu...

Pathophysiologically, the organism colonizes superficial epithelial tissues, enabling persistent transmission to susceptible populations through respiratory droplets or direct exudative contact despite the presence of circulating host antitoxin antibodies

Eradication is targeted via antimicrobial therapy to eliminate carriage and halt secondary spread within public health settings

Eradication is targeted via antimicrobial therapy to eliminate carriage and halt secondary spread within public health settings

Eradication is targeted via antimicrobial therapy to eliminate carriage and halt secondary spread within public health settings