Diphtheroid prosthetic heart valve endocarditis

Diphtheroid prosthetic heart valve endocarditis is a severe, life-threatening cardiovascular infection occurring on mechanical or bioprosthetic cardiac valves caused by diphtheroids, which are non-diphtherial *Corynebacterium* species and related coryneform bacteria Diagnosis is clinically challenging because these skin and mucous membrane commensals are frequently misidentified as blood culture contaminants, yet they frequently display multidrug resistance that complicates management

Diphtheroid prosthetic heart valve endocarditis is a severe, life-threatening cardiovascular infection occurring on mechanical or bioprosthetic cardiac valves caused by diphtheroids, which are non-diphtherial *Corynebacterium* species and related coryneform bacteria Primarily affecting adults with prior valve replacement surgery, the condition frequently manifests early in the postoperative period following intraoperative contamination or nosocomial bacteremia Pathophysiologically, these organis...

Diphtheroid prosthetic heart valve endocarditis is a severe, life-threatening cardiovascular infection occurring on mechanical or bioprosthetic cardiac valves caused by diphtheroids, which are non-diphtherial *Corynebacterium* species and related coryneform bacteria

Primarily affecting adults with prior valve replacement surgery, the condition frequently manifests early in the postoperative period following intraoperative contamination or nosocomial bacteremia Pathophysiologically, these organisms colonize the artificial sewing ring or leaflet materials, forming adherent biofilms and vegetations that often invade the cardiac annulus to cause valvular dysfunction, perivalvular abscesses, prosthetic dehiscence, and systemic embolization

Pathophysiologically, these organisms colonize the artificial sewing ring or leaflet materials, forming adherent biofilms and vegetations that often invade the cardiac annulus to cause valvular dysfunction, perivalvular abscesses, prosthetic dehiscence, and systemic embolization

Diagnosis is clinically challenging because these skin and mucous membrane commensals are frequently misidentified as blood culture contaminants

Diagnosis is clinically challenging because these skin and mucous membrane commensals are frequently misidentified as blood culture contaminants

Diagnosis is clinically challenging because these skin and mucous membrane commensals are frequently misidentified as blood culture contaminants, yet they frequently display multidrug resistance that complicates management