Duchenne muscular dystrophy

Duchenne muscular dystrophy is a severe, rapidly progressive X-linked recessive neuromuscular disorder caused by mutations in the *DMD* gene that result in an absence or critical deficiency of the functional structural protein dystrophin Primarily affecting males with early childhood onset, the lack of dystrophin compromises the sarcolemmal integrity of skeletal and cardiac muscle, rendering fibers susceptible to contraction-induced mechanical damage, chronic necrosis, inflammation, and progress...

Duchenne muscular dystrophy is a severe, rapidly progressive X-linked recessive neuromuscular disorder caused by mutations in the *DMD* gene that result in an absence or critical deficiency of the functional structural protein dystrophin Primarily affecting males with early childhood onset, the lack of dystrophin compromises the sarcolemmal integrity of skeletal and cardiac muscle, rendering fibers susceptible to contraction-induced mechanical damage, chronic necrosis, inflammation, and progress...

Duchenne muscular dystrophy is a severe, rapidly progressive X-linked recessive neuromuscular disorder caused by mutations in the *DMD* gene that result in an absence or critical deficiency of the functional structural protein dystrophin Primarily affecting males with early childhood onset, the lack of dystrophin compromises the sarcolemmal integrity of skeletal and cardiac muscle, rendering fibers susceptible to contraction-induced mechanical damage, chronic necrosis, inflammation, and progress...