Indication

E. coli infection

An *E. Read more about E. coli infection

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About E. coli infection.

An *E.

coli* infection is an infectious disease caused by pathogenic strains of *Escherichia coli*, a Gram-negative bacterium that commonly colonizes the healthy human gastrointestinal tract.

While most strains are harmless commensals, virulent pathotypes can affect multiple body systems across all age groups, most frequently manifesting as acute diarrheal illness, urinary tract infections, intra-abdominal infections, neonatal meningitis, or bloodstream sepsis.

Pathophysiologically, disease occurs via specific virulence mechanisms, including cellular adhesion, enterotoxin or Shiga toxin production, and mucosal invasion.

Clinical presentations range from self-limiting watery diarrhea and abdominal cramping to dysentery, pyelonephritis, or severe systemic complications such as hemolytic uremic syndrome.

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