E. coli septic arthritis

*E. coli* septic arthritis is an acute, potentially destructive bacterial infection of the synovial joint space caused by the Gram-negative bacillus *Escherichia coli* It most commonly affects large weight-bearing joints—such as the knee or hip—and predominantly occurs in older adults, immunocompromised individuals, or patients with pre-existing joint disease or recent invasive urologic procedures

*E. coli* septic arthritis is an acute, potentially destructive bacterial infection of the synovial joint space caused by the Gram-negative bacillus *Escherichia coli* It most commonly affects large weight-bearing joints—such as the knee or hip—and predominantly occurs in older adults, immunocompromised individuals, or patients with pre-existing joint disease or recent invasive urologic procedures

It most commonly affects large weight-bearing joints—such as the knee or hip—and predominantly occurs in older adults, immunocompromised individuals, or patients with pre-existing joint disease or recent invasive urologic procedures

Pathophysiologically, the organism typically seeds the vascular synovial membrane via hematogenous dissemination from a primary urinary tract or gastrointestinal source, though it may also arise from direct inoculation

Pathophysiologically, the organism typically seeds the vascular synovial membrane via hematogenous dissemination from a primary urinary tract or gastrointestinal source, though it may also arise from direct inoculation

The infection manifests clinically with rapid-onset severe joint pain, swelling, erythema, localized warmth, and restricted range of motion, frequently accompanied by fever and marked purulent synovial fluid effusion

The infection manifests clinically with rapid-onset severe joint pain, swelling, erythema, localized warmth, and restricted range of motion, frequently accompanied by fever and marked purulent synovial fluid effusion

The infection manifests clinically with rapid-onset severe joint pain, swelling, erythema, localized warmth, and restricted range of motion, frequently accompanied by fever and marked purulent synovial fluid effusion