Ecthyma gangrenosum

Ecthyma gangrenosum is a rare, severe cutaneous manifestation typically associated with systemic bacteremia, classic to *Pseudomonas aeruginosa* infection, though occasionally caused by other opportunistic pathogens It predominantly affects the integumentary system of severely immunocompromised, neutropenic, or critically ill patients

Ecthyma gangrenosum is a rare, severe cutaneous manifestation typically associated with systemic bacteremia, classic to *Pseudomonas aeruginosa* infection, though occasionally caused by other opportunistic pathogens Pathophysiologically, hematogenous bacterial seeding leads to perivascular invasion of dermal and subcutaneous blood vessels, resulting in necrotizing vasculitis, secondary thrombosis, and localized tissue infarction Clinically, the condition manifests as painless erythematous macule...

It predominantly affects the integumentary system of severely immunocompromised, neutropenic, or critically ill patients Pathophysiologically, hematogenous bacterial seeding leads to perivascular invasion of dermal and subcutaneous blood vessels, resulting in necrotizing vasculitis, secondary thrombosis, and localized tissue infarction

Clinically, the condition manifests as painless erythematous macules or hemorrhagic bullae that rapidly progress into painless, punched-out necrotic ulcers covered by a central black eschar with an erythematous rim