Gastric cancer

Gastric cancer is a malignant neoplastic disease that originates in the mucosal lining of the stomach, most commonly manifesting as adenocarcinoma

Gastric cancer is a malignant neoplastic disease that originates in the mucosal lining of the stomach, most commonly manifesting as adenocarcinoma Pathophysiologically, it is broadly classified into intestinal and diffuse histological subtypes, characterized by glandular formation or diffuse, infiltrative signet-ring cells, respectively

It affects the upper gastrointestinal system and predominantly occurs in older adults, frequently developing through a prolonged inflammatory cascade associated with *Helicobacter pylori* infection, dietary exposures, or inherited genetic predispositions Pathophysiologically, it is broadly classified into intestinal and diffuse histological subtypes, characterized by glandular formation or diffuse, infiltrative signet-ring cells, respectively

It affects the upper gastrointestinal system and predominantly occurs in older adults, frequently developing through a prolonged inflammatory cascade associated with *Helicobacter pylori* infection, dietary exposures, or inherited genetic predispositions

It affects the upper gastrointestinal system and predominantly occurs in older adults, frequently developing through a prolonged inflammatory cascade associated with *Helicobacter pylori* infection, dietary exposures, or inherited genetic predispositions While early stages are typically asymptomatic or non-specific, disease progression is clinically characterized by persistent epigastric pain, early satiety, progressive dysphagia, hematemesis, melena, and profound involuntary weight loss

While early stages are typically asymptomatic or non-specific, disease progression is clinically characterized by persistent epigastric pain, early satiety, progressive dysphagia, hematemesis, melena, and profound involuntary weight loss